ea0073aep475 | Pituitary and Neuroendocrinology | ECE2021
Feola Tiziana
, Santopietro Michelina
, Arosio Maura
, Palumbo Giovanna
, Giona Fiorina
, Marie-Lise Jaffrain-Rea
IntroductionLangherans Cell Histiocytosis (LCH) is a rare disease due to a neoplastic proliferation of Langerhans-type cells. Hypothalamic-pituitary (HP) involvement may occur in 2040% of the patients, presenting with diabetes insipidus (DI) and/or anterior pituitary dysfunction. Typically, such abnormalities are permanent and unresponsive to systemic treatment of LCH. We report the case of a young woman with pulmonary and HP localizations, and sig...